Author: Dr. Paul Kwik D.C.

Chiropractor, Functional Health Doctor, EMF Remediation Specialist
📩 [Contact for personalized health plans]

When someone is newly diagnosed with high blood sugar or diabetes and begins medication, it’s not uncommon for them to notice changes in their appetite. One common scenario is a sudden loss of appetite after starting Jardiance and metformin—two frequently prescribed medications. So, what causes this, and should you be concerned?

Let’s break it down.

🧪 1. Metformin: A Common Appetite Suppressant

Metformin is often the first-line medication for type 2 diabetes. It’s highly effective, but one of the most well-known side effects is gastrointestinal distress. This can include:

Nausea
Bloating or abdominal discomfort
Diarrhea
A metallic taste in the mouth
Loss of appetite

These effects are most pronounced when first starting the medication or when the dose increases. For some people, the appetite suppression continues even after other side effects subside.

💡 Tip: Extended-release versions of metformin (like Glucophage XR) may reduce these side effects.

💧 2. Jardiance: Less Likely but Still a Factor

Jardiance (empagliflozin) helps lower blood sugar by removing excess glucose through urine. While it’s not primarily known for appetite suppression, it can indirectly reduce hunger due to:

Mild dehydration (from increased urination)
Weight loss effects
Altered metabolism and blood sugar dynamics

Some users report feeling full faster or having reduced interest in food.

🏥 3. The Impact of Hospitalization and Blood Sugar Shifts

If a person was hospitalized for high blood sugar, they may still be recovering physically and emotionally, which can blunt appetite. Factors that contribute include:

Electrolyte imbalances
Fatigue
Stress or trauma
Changes in routine or digestion

Even after discharge, the body may need time to fully stabilize.

⚠️ 4. A Word of Caution: Watch for Signs of DKA

Though rare, especially with Jardiance, some people can develop a serious condition called euglycemic diabetic ketoacidosis (DKA). This condition can occur even when blood sugar levels aren’t extremely high.

🚨 Signs to watch for: