When someone is newly diagnosed with high blood sugar or diabetes and begins medication, it’s not uncommon for them to notice changes in their appetite. One common scenario is a sudden loss of appetite after starting Jardiance and metformin—two frequently prescribed medications. So, what causes this, and should you be concerned?

Let’s break it down.

🧪 1. Metformin: A Common Appetite Suppressant

Metformin is often the first-line medication for type 2 diabetes. It’s highly effective, but one of the most well-known side effects is gastrointestinal distress. This can include:

Nausea
Bloating or abdominal discomfort
Diarrhea
A metallic taste in the mouth
Loss of appetite

These effects are most pronounced when first starting the medication or when the dose increases. For some people, the appetite suppression continues even after other side effects subside.

💡 Tip: Extended-release versions of metformin (like Glucophage XR) may reduce these side effects.

💧 2. Jardiance: Less Likely but Still a Factor

Jardiance (empagliflozin) helps lower blood sugar by removing excess glucose through urine. While it’s not primarily known for appetite suppression, it can indirectly reduce hunger due to:

Mild dehydration (from increased urination)
Weight loss effects
Altered metabolism and blood sugar dynamics

Some users report feeling full faster or having reduced interest in food.

🏥 3. The Impact of Hospitalization and Blood Sugar Shifts

If a person was hospitalized for high blood sugar, they may still be recovering physically and emotionally, which can blunt appetite. Factors that contribute include:

Electrolyte imbalances
Fatigue
Stress or trauma
Changes in routine or digestion

Even after discharge, the body may need time to fully stabilize.

⚠️ 4. A Word of Caution: Watch for Signs of DKA

Though rare, especially with Jardiance, some people can develop a serious condition called euglycemic diabetic ketoacidosis (DKA). This condition can occur even when blood sugar levels aren’t extremely high.

🚨 Signs to watch for:

Persistent nausea or vomiting
Abdominal pain
Fruity breath odor
Fatigue or confusion
Loss of appetite

If any of these are present, seek medical attention immediately.

✅ What You Can Do

🌿 Natural Remedies to Help Restore Appetite & Reduce Discomfort

Here are gentle, natural ways to support recovery and ease symptoms:

🍋 1. Ginger Tea or Capsules

Benefits: Reduces nausea, improves digestion
Use: Sip fresh ginger tea before meals or take 500–1000 mg ginger extract daily

🍎 2. Apple Cider Vinegar

Benefits: Supports digestion and blood sugar balance
Use: Mix 1 tsp in warm water before meals (check with your doctor first)

🌱 3. Bitter Herbs (Gentian, Dandelion Root)

Benefits: Stimulate appetite and bile flow
Use: Take as tincture or tea 10–15 minutes before meals

🧂 4. Electrolyte-Rich Fluids

Benefits: Rehydrates and improves energy if Jardiance causes fluid loss
Use: Coconut water, bone broth, or a natural electrolyte drink with no added sugar

🥬 5. Small, Nutrient-Dense Meals

Benefits: Prevents overwhelm and ensures calorie intake
Ideas:
- Avocado on sourdough
- Smoothies with protein, berries, and flax
- Bone broth with soft-cooked veggies
- Hard-boiled eggs and cucumber slices

🧘 6. Gentle Movement

Benefits: Stimulates digestion and mood
Try: A short walk after meals, yoga, or stretching

🌞 7. Sunlight & Vitamin D

Benefits: Can improve mood and appetite naturally
Use: Aim for 10–20 minutes of natural light daily

✅ Final Recommendations

If you or a loved one experiences ongoing appetite loss after starting Jardiance and metformin:

Speak with a healthcare provider about medication timing or dose adjustments
Hydrate consistently
Rule out more serious causes like DKA
Try gentle, natural remedies to encourage hunger and reduce discomfort

💬 Let’s Talk

Have you tried any of these remedies or experienced similar side effects? Share your experience or ask questions in the comments below.

If you or someone you love is struggling with appetite after starting Jardiance and metformin:

Speak with your healthcare provider. They may adjust the dosage or recommend a different formulation.
Stay hydrated. Dehydration can blunt appetite and cause fatigue.
Monitor for serious symptoms. Don’t ignore persistent nausea or extreme fatigue.
Track your meals. Sometimes small, frequent meals are easier than forcing full portions.

Final Thoughts

While loss of appetite on these medications isn't unusual, it shouldn't be ignored—especially if it interferes with nutrition or points to something more serious. With medical guidance and small adjustments, most people can find a balance that helps them feel better while keeping their blood sugar under control.